威斯尼斯人wns888app官方版前期专注于肿瘤药效评价，后续会逐步在自身免疫性疾病、代谢紊乱性疾病以及神经性疾病进行拓展。目前已积累了大量肿瘤药效评价模型：Syngeneic及CDX模型数~100个；PDX模型数200+个；人源化模型数~10个。
| 肿瘤类型 |
Syngeneic model |
CDX model |
| 肝癌 | H22,Hepa1-6 |
SNU398,SNU398-CXCR2,
Huh7,SK-HEP-1,HepG2,Hep3B |
| 肠癌 | CT26.WT,MC38 |
Caco2,SW480,HCT-116,LOVO,RKO,HT-29,
SW620,DLD-1,COLO205,LOVO,KM12,HCT-15 |
| 胃癌 | MFC | NCI-N87,KATO III,HGC-27,AGS,MKN45,SNU16 |
| 肺癌 | LLC |
Calu-3,NCI-H1975,NCI-H446,A427,
A549,SHP-77,SH-MES-1,NCI-H1299,HCC827 |
| 血液瘤 | L1210,A20 |
Raji,Daudi,MOLT-4,THP-1,K562,NALM-6,SU-DHL-1,RL,HL-60,
Jeko-1,KG-1,MM.1S,MM.1R,RPMI 8226,KMS-11,OPM-2,NCI-H929 |
| 胰腺癌 | Pan02,LTPA | MIA PaCa2,PANC1,BxPc-3,Capan-2 |
| 乳腺癌 | 4T-1 |
MCF-7,MDA-MB-231,MDA-MB-468,
HCC-1806,HCC-1954,JIMT-1,MDA-MB-436 |
| 前列腺癌 | / | Lncap,PC-3,DU145,RM-1,22RV.1,VCaP |
| 卵巢癌 | / | SK-OV-3,OVCAR-3,A2780,TOV-21G,OV-90 |
| 肾癌 | / | A498,769-P,786-O,G401,G402,Caki-1, |
| 黑色素瘤 | B16F10 | A375,SK-MEL-28 |
| 神经胶质瘤 | / | U87-MG,U251,LN299 |
| 其他癌种 | K7M2-WT(骨肉瘤) | Hela(宫颈癌),A-431(皮肤癌),KYSE-30(食管鳞癌) |
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